Intestinal response to growth factors administered alone or in combination with human [Gly2]glucagon-like peptide 2.

  title={Intestinal response to growth factors administered alone or in combination with human [Gly2]glucagon-like peptide 2.},
  author={Daniel J Drucker and Lorraine Deforest and Patricia L Brubaker},
  journal={American journal of physiology. Gastrointestinal and liver physiology},
  volume={273 6},
The control of intestinal epithelial growth is regulated by interactions of growth factors in various cellular compartments of the small and large bowel. Little information is available on the intestinal growth response to combinations of growth factors. We studied the intestinotrophic properties of a dipeptidyl peptidase IV resistant glucagon-like peptide 2 (GLP-2) analog, human [Gly2]GLP-2 (h[Gly2]GLP-2), as well as of epidermal growth factor (EGF), long [Arg3]insulin-like growth factor I… CONTINUE READING
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