Intestinal permeability and systemic infections in critically ill patients: Effect of glutamine*

@article{DeSouza2005IntestinalPA,
  title={Intestinal permeability and systemic infections in critically ill patients: Effect of glutamine*},
  author={D. A. De-Souza and L. Greene},
  journal={Critical Care Medicine},
  year={2005},
  volume={33},
  pages={1125-1135}
}
Objective:This article provides a critical review of the evidence indicating that an increase in intestinal permeability is associated with the installation of bacteremia, sepsis, and the multiple organ failure syndrome and that glutamine in pharmacologic doses reduces the acute increase of intestinal permeability and the infection frequency in critically ill patients. Data Source:All studies published until December 2004 about intestinal permeability, bacterial translocation, and glutamine… Expand
247 Citations

Paper Mentions

Interventional Clinical Trial
This study aims to describe the use of glutamine supplementation in the modulation of inflammatory response in critically ill pediatric patients and to determine if this decrease… Expand
ConditionsInflammatory Response, Multi-organ Failure
InterventionDietary Supplement
Interventional Clinical Trial
Glutamine is an amino acid which is rapidly depleted in critical illness. It is used as energy by cells that line the gut, vital for immune system function, and works as an anti… Expand
ConditionsCritical Illness, Respiratory Insufficiency, Sepsis
InterventionDrug
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References

SHOWING 1-10 OF 117 REFERENCES
Intestinal permeability in the critically ill
Bacterial translocation and enteral nutrition in humans: an outsider looks in.
  • T. Lipman
  • Biology, Medicine
  • JPEN. Journal of parenteral and enteral nutrition
  • 1995
The prevalence of gut translocation in humans.
Glutamine supplementation in serious illness: A systematic review of the evidence*
Effect of long-term oral glutamine supplements on small intestinal permeability in patients with Crohn's disease.
...
1
2
3
4
5
...