Intestinal mucosal microdialysis: Histamine release in splanchnic ischemia/reperfusion injury in piglets

Splanchnic ischemia is common in critically ill patients. It can occur in conjunction with trauma, cardiac surgery, sepsis and pancreatitis. The role of histamine in ischemia/ reperfusion (I/R) injury in splanchnic circulation has not received much interest until recently. Studies have mainly focused on plasma or blood levels of histamine. We have used… CONTINUE READING