Intestinal microvascular adaptation to chronic portal hypertension in the rat.

@article{Benoit1988IntestinalMA,
  title={Intestinal microvascular adaptation to chronic portal hypertension in the rat.},
  author={Joseph N. Benoit and Dr. D. Neil Granger},
  journal={Gastroenterology},
  year={1988},
  volume={94 2},
  pages={471-6}
}
Microvascular pressures, diameters, and flow velocities were measured in the small intestine of rats with chronic stenosis of the portal vein. Ten days after portal vein stenosis, portal venous pressure increased (13.8 +/- 0.4 mmHg vs, 7.3 +/- 0.5 mmHg; p less than 0.05) whereas systemic arterial pressure decreased (94.2 +/- 2.0 mmHg vs. 106.5 +/- 1.6 mmHg; p less than 0.05). Red blood cell centerline velocity, measured in first-order arterioles, was significantly higher in portal hypertensive… CONTINUE READING

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