Intestinal microflora in early infancy: composition and development

  title={Intestinal microflora in early infancy: composition and development},
  author={Silvia Fanaro and Roberta Chierici and Pietro Guerrini and Vittorio Vigi},
  journal={Acta P{\ae}diatrica},
The neonatal intestinal microbiota is a complex ecosystem composed of numerous genera, species and strains of bacteria. This enormous cell mass performs a variety of unique activities that affect both the colonic and systemic physiology. Its primary activities include nutritive, metabolic, immunological and protective functions. Most studies of infants have been based on faecal samples using the classical plating techniques with culturing on specific media. The limitations of these methods must… 
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The impact of antibiotics on the establishment of the infant gut resistome, and on the role of the microbiota as a reservoir of resistance genes, should be evaluated in the context of the problems associated with the increasing number of antibiotic resistant pathogenic strains.


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The intestinal microflora in early life has certain features that may make the infant vulnerable to infections and might be of importance for the maturation of the gut immune system, including the development of oral tolerance to harmless antigens such as food proteins.
Developmental microbial ecology of the neonatal gastrointestinal tract.
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This report deals with the intestinal colonization of breast-fed village children studied in their own environment by means of a design that retains at a minimum disturbance of the customs and living conditions of the inhabitants, and concerns the anaerobic and facultative flora, with some emphasis on the E. coli group.
Molecular assessment of intestinal microflora.
  • G. Tannock
  • Biology
    The American journal of clinical nutrition
  • 2001
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By combining the rationale of pro- and prebiotics, the concept of synbiotics is proposed to characterize some colonic foods with interesting nutritional properties that make these compounds candidates for classification as health-enhancing functional food ingredients.
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Development of Intestinal Microbiota
Fecal microflora in healthy infants born by different methods of delivery: permanent changes in intestinal flora after cesarean delivery.
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