Intestinal fibrovascular nodules caused by Schistosoma mansoni infection in Calomys callosus Rengger, 1830 (Rodentia: Cricetidae): a model of concomitant fibrosis and angiogenesis.

@article{Lenzi2002IntestinalFN,
  title={Intestinal fibrovascular nodules caused by Schistosoma mansoni infection in Calomys callosus Rengger, 1830 (Rodentia: Cricetidae): a model of concomitant fibrosis and angiogenesis.},
  author={Jane A Lenzi and {\'E}ster Maria Mota and Marcelo Pelajo-Machado and Leandro S Vale and Bruno Silva Vale and Zilton de Ara{\'u}jo Andrade and Henrique Leonel Lenzi},
  journal={Memorias do Instituto Oswaldo Cruz},
  year={2002},
  volume={97 Suppl 1},
  pages={117-27}
}
Human schistosomiasis develops extensive and dense fibrosis in portal space, together with congested new blood vessels. This study demonstrates that Calomys callosus infected with Schistosoma mansoni also develops fibrovascular lesions, which are found in intestinal subserosa. Animals were percutaneously infected with 70 cercariae and necropsied at 42, 45, 55, 80, 90 and 160 days after infection. Intestinal sections were stained for brightfield, polarization microscopy, confocal laser scanning… CONTINUE READING