Intestinal fibrosis in IBD—a dynamic, multifactorial process

  title={Intestinal fibrosis in IBD—a dynamic, multifactorial process},
  author={F Rieder and Claudio Fiocchi},
  journal={Nature Reviews Gastroenterology &Hepatology},
Intestinal fibrosis is a common and potentially serious complication of IBD that results from the reaction of intestinal tissue to the damage inflicted by chronic inflammation. The traditional view that fibrosis is inevitable or irreversible in patients with IBD is progressively changing in light of improved understanding of the cellular and molecular mechanisms that underlie the pathogenesis of fibrosis in general, and, in particular, intestinal fibrosis. These mechanisms are complex and… CONTINUE READING

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