Intestinal expression and cellular immune responses to human heat-shock protein 60 in Crohn's disease

@article{BacaEstrada2005IntestinalEA,
  title={Intestinal expression and cellular immune responses to human heat-shock protein 60 in Crohn's disease},
  author={Maria E. Baca-Estrada and Radhey S. Gupta and Ronald H. Stead and Kenneth Croitoru},
  journal={Digestive Diseases and Sciences},
  year={2005},
  volume={39},
  pages={498-506}
}
Changes in the intestinal expression of the endogenous human 60-kDa heat-shock protein (HSP60) were investigated in patients with Crohn's disease. HSP60 immunoreactivity was detected in epithelial cells, vascular smooth muscle, and nerve cell bodies of both small and large bowel from patients with Crohn's disease. However, control tissue showed a similar pattern of HSP60 expression. Western blot analysis confirmed that the HSP60 immunoreactivity detected in the intestine corresponded to the 60… Expand
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