Intestinal epithelial differentiation: new insights from chimeric and transgenic mice

@article{Gordon1989IntestinalED,
  title={Intestinal epithelial differentiation: new insights from chimeric and transgenic mice},
  author={Jeffrey I. Gordon},
  journal={The Journal of Cell Biology},
  year={1989},
  volume={108},
  pages={1187 - 1194}
}
T H E mammalian intestinal epithelium represents a unique model system for studying cellular differentiation since it undergoes continuous and rapid renewal. Perpetual differentiation results in the generation of its four principal cell types, each with a unique phenotype. The processes of proliferation and cellular differentiation are topologically very well organized. Gradients in gene expression are established and maintained in several spatial dimensions within this epithelium. Recent… CONTINUE READING

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Charac - terization of rat cellular retinol binding protein II expressed in E . coll

M. Sargiacoma, L. Graeve, A. K. Saltiel, E. Rodriguez-Boulan
  • J . Biol . Chem .
  • 1988