Intestinal epithelial barrier and mucosal immunity

  title={Intestinal epithelial barrier and mucosal immunity},
  author={Claudia M{\"u}ller and I. Autenrieth and Andreas Peschel},
  journal={Cellular and Molecular Life Sciences},
Abstract.The innate immune system plays a crucial role in maintaining the integrity of the intestine and protecting the host against a vast number of potential microbial pathogens from resident and transient gut microflora. Mucosal epithelial cells and Paneth cells produce a variety of antimicrobial peptides (defensins, cathelicidins, crytdinrelated sequence peptides, bactericidal/permeabilityincreasing protein, chemokine CCL20) and bacteriolytic enzymes (lysozyme, group IIA phospholipase A2… CONTINUE READING

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