Intestinal disaccharidase activities and activity ratios in a group of 60 adult German subjects.

@article{Howell1980IntestinalDA,
  title={Intestinal disaccharidase activities and activity ratios in a group of 60 adult German subjects.},
  author={John N. Howell and J R Mellmann and P N Ehlers and Gebhard Flatz},
  journal={Hepato-gastroenterology},
  year={1980},
  volume={27 3},
  pages={208-12}
}
Lactase, maltase and sucrase activities were determined in samples of jejunal mucosa obtained by suction biopsy from 60 healthy adult German males. Primary adult hypolactasia ("lactase deficiency") was found in 8 subjects (13%). Maltase:lactase and sucrase:lactase activity ratios were significantly higher in post-weaning hypolactasia than in adult lactase persistence. Sources of variation in disaccharidase activities measured in biopsy tissue homogenates are discussed.