Intestinal colonization of infant hamsters with Clostridium difficile.

  title={Intestinal colonization of infant hamsters with Clostridium difficile.},
  author={Rial D. Rolfe and Joseph P. Iaconis},
  journal={Infection and immunity},
  volume={42 2},
Infant hamsters of different ages were examined for their susceptibility to enteric Clostridium difficile colonization. Intragastric administration of C. difficile to infant hamsters resulted in multiplication of the organism in the intestinal tracts of animals 4 to 12 days old; hamsters younger or older were resistant to C. difficile intestinal colonization. Toxicity to the colonized animals could not be demonstrated despite cytotoxin titers in some infant hamsters comparable to titers found… CONTINUE READING