Intestinal calcium absorption: Molecular vitamin D mediated mechanisms

@article{Bouillon2003IntestinalCA,
  title={Intestinal calcium absorption: Molecular vitamin D mediated mechanisms},
  author={Roger Bouillon and SJ Van Cromphaut and Geert Carmeliet},
  journal={Journal of Cellular Biochemistry},
  year={2003},
  volume={88}
}
Rickets and hyperparathyroidism caused by a defective Vitamin D receptor (VDR) can be prevented in humans and animals by high calcium intake, suggesting that intestinal calcium absorption is critical for 1,25(OH)2 vitamin D [1,25‐(OH)2D3] action on calcium homeostasis. We assessed the rate of serum 45Ca accumulation within 10 min after oral gavage in two strains of VDR‐knock out (KO) mice (Leuven and Tokyo KO) and observed a threefold lower area under the curve in both KO‐strains. Moreover, we… 
Molecular mechanisms for regulation of intestinal calcium absorption by vitamin D and other factors
  • J. Fleet, R. Schoch
  • Biology, Medicine
    Critical reviews in clinical laboratory sciences
  • 2010
Optimal intestinal calcium (Ca) absorption is necessary for the protection of bone and the prevention of osteoporosis. Ca absorption can be represented as the sum of a saturable pathway and a
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TLDR
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