Intestinal anaphylaxis in the rat: jejunal response to in vitro antigen exposure.

@article{Perdue1986IntestinalAI,
  title={Intestinal anaphylaxis in the rat: jejunal response to in vitro antigen exposure.},
  author={Mary H. Perdue and Dietrich Gall},
  journal={The American journal of physiology},
  year={1986},
  volume={250 4 Pt 1},
  pages={G427-31}
}
In previous studies we showed that rats sensitized to egg albumin respond to in vivo intraluminal antigen with decreased net absorption of Na+, Cl-, and water. These abnormalities are associated with high serum levels of immunoglobulin E (IgE) antibodies and mucosal mast cell degranulation. In the present in vitro study electrical parameters, unidirectional fluxes of Na+ and Cl-, and levels of cAMP were determined in jejunum from sensitized and control rats during a basal period and after… CONTINUE READING