Intestinal adaptation is stimulated by partial enteral nutrition supplemented with the prebiotic short-chain fructooligosaccharide in a neonatal intestinal failure piglet model.

@article{Barnes2012IntestinalAI,
  title={Intestinal adaptation is stimulated by partial enteral nutrition supplemented with the prebiotic short-chain fructooligosaccharide in a neonatal intestinal failure piglet model.},
  author={Jennifer L Barnes and Brigitta Hartmann and Jens Juul Holst and Kelly Anne. Tappenden},
  journal={JPEN. Journal of parenteral and enteral nutrition},
  year={2012},
  volume={36 5},
  pages={
          524-37
        }
}
BACKGROUND Butyrate has been shown to stimulate intestinal adaptation when added to parenteral nutrition (PN) following small bowel resection but is not available in current PN formulations. The authors hypothesized that pre- and probiotic administration may be a clinically feasible method to administer butyrate and stimulate intestinal adaptation. METHODS AND MATERIALS Neonatal piglets (48 hours old, n = 87) underwent placement of a jugular catheter and an 80% jejunoileal resection and were… CONTINUE READING
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