Intestinal absorption of sodium and nitric oxide-dependent vasodilation interact to dominate resting vascular resistance.

@article{Bohlen1996IntestinalAO,
  title={Intestinal absorption of sodium and nitric oxide-dependent vasodilation interact to dominate resting vascular resistance.},
  author={H. Glenn Bohlen and Julia M. Lash},
  journal={Circulation research},
  year={1996},
  volume={78 2},
  pages={231-7}
}
The villi of the small intestine maintain a hypertonic interstitium at all times, and the submucosal glands constantly secrete ions and accompanying water into the lumen. Generation of the 400- to 600-mOsm interstitial fluid in the villus and secretion by glands may require a large expenditure of energy and, consequently, have major effects on intestinal vascular regulation to supply oxygen and nutrients. Blood flow and oxygen consumption were measured in the ileum of anesthetized rats during… CONTINUE READING

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