Intestinal absorption of polyenephosphatidylcholine in man.

  title={Intestinal absorption of polyenephosphatidylcholine in man.},
  author={O Zierenberg and Scott M Grundy},
  journal={Journal of lipid research},
  volume={23 8},
The metabolic fate of 1 of 3H/14C-labeled dilinoleoglycerophosphocholine was studied in five patients after oral administration. The 3H label was in choline and 14C was in the two linoleic acid residues. More than 90% of both isotopes was absorbed from the intestine. Seventy to 90% of the 3H radioactivity in blood was linked to phosphatidylcholine (PC) whereas 14C was associated with both PC and nonpolar lipids. At peak activity, the 3H/14C ratio of plasma PC was twice that of oral PC; this… CONTINUE READING