Intestinal absorption of S-nitrosothiols: Permeability and transport mechanisms.

@article{Bonetti2018IntestinalAO,
  title={Intestinal absorption of S-nitrosothiols: Permeability and transport mechanisms.},
  author={Justine Bonetti and Yi Zhou and Marianne Parent and I Clarot and Haiyan Yu and Isabelle Fries-Raeth and Pierre Leroy and Isabelle Lartaud and Caroline Gaucher},
  journal={Biochemical pharmacology},
  year={2018},
  volume={155},
  pages={
          21-31
        }
}
S-Nitrosothiols, a class of NO donors, demonstrate potential benefits for cardiovascular diseases. Drugs for such chronic diseases require long term administration preferentially through the oral route. However, the absorption of S-nitrosothiols by the intestine, which is the first limiting barrier for their vascular bioavailability, is rarely evaluated… CONTINUE READING