Intestinal absorption of 25-hydroxyvitamin D and osteomalacia in primary biliary cirrhosis.

@article{Compston1977IntestinalAO,
  title={Intestinal absorption of 25-hydroxyvitamin D and osteomalacia in primary biliary cirrhosis.},
  author={Juliet E Compston and R. P. Thompson},
  journal={Lancet},
  year={1977},
  volume={1 8014},
  pages={721-4}
}
Bone histology and intestinal absorption of 25-hydroxyvitamin D3 (25-OHD) were investigated in 11 patients with primary biliary cirrhosis (P.B.C.). 4 patients had osteomalacia, and all these had received long-term cholestyramine. Plasma-25-hydroxyvitamin-D (25-OHD) concentrations after an oral dose of 25-OHD3 were significantly lower in the patients with P.B.C. (especially those with osteomalacia) than in normal controls. Serum calcium and urinary calcium excretion were lower, and serum… CONTINUE READING

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