Intestinal Na-P(i) cotransporter adaptation to dietary P(i) content in vitamin D receptor null mice.

@article{Segawa2004IntestinalNC,
  title={Intestinal Na-P(i) cotransporter adaptation to dietary P(i) content in vitamin D receptor null mice.},
  author={Hiroko Segawa and Ichiro Kaneko and Setsuko Yamanaka and Mikiko Ito and M Kuwahata and Yoshio Inoue and Shigeaki Kato and Ken-Ichi Miyamoto},
  journal={American journal of physiology. Renal physiology},
  year={2004},
  volume={287 1},
  pages={
          F39-47
        }
}
Recent studies suggest that vitamin D may play a role in intestinal Na(+)-dependent phosphate transport adaptation to variable levels of dietary P(i). Therefore, the goal of the current study was to assess Na(+)-dependent P(i) cotransport activity in transgenic mice to determine whether vitamin D is an essential mediator of this process. Intestinal brush-border membrane (BBM), Na(+)-dependent P(i) cotransport activity was significantly decreased in vitamin D receptor (VDR) null [VDR (-/-)] mice… 
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