Intestinal Inflammation and Mucosal Barrier Function

@article{Medina2014IntestinalIA,
  title={Intestinal Inflammation and Mucosal Barrier Function},
  author={F. S{\'a}nchez de Medina and I. Romero-Calvo and Cristina Mascaraque and O. Mart{\'i}nez-Augustin},
  journal={Inflammatory Bowel Diseases},
  year={2014},
  volume={20},
  pages={2394–2404}
}
  • F. Sánchez de Medina, I. Romero-Calvo, +1 author O. Martínez-Augustin
  • Published 2014
  • Biology, Medicine
  • Inflammatory Bowel Diseases
    • Abstract:Intestinal mucosal barrier function is the capacity of the intestine to provide adequate containment of luminal microorganisms and molecules while preserving the ability to absorb nutrients. The central element is the epithelial layer, which physically separates the lumen and the internal milieu and is in charge of vectorial transport of ions, nutrients, and other substances. The secretion of mucus-forming mucins, sIgA, and antimicrobial peptides reinforces the mucosal barrier on the… CONTINUE READING
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    References

    Publications referenced by this paper.
    SHOWING 1-10 OF 102 REFERENCES
    Regulation of intestinal epithelial permeability by tight junctions
    • 510
    • Highly Influential
    Modulation of intestinal barrier by intestinal microbiota: pathological and therapeutic implications.
    • 159
    Epithelial NEMO links innate immunity to chronic intestinal inflammation
    • 927
    • PDF
    The Antibacterial Lectin RegIIIγ Promotes the Spatial Segregation of Microbiota and Host in the Intestine
    • 823
    • PDF
    Toll-like receptor 2 controls mucosal inflammation by regulating epithelial barrier function.
    • 550
    Wound healing of intestinal epithelial cells.
    • 167
    The Role of Macrophages and Dendritic Cells in the Initiation of Inflammation in IBD
    • 119
    The role of pattern recognition receptors in intestinal inflammation
    • 120
    • Highly Influential
    Metabolites produced by commensal bacteria promote peripheral regulatory T cell generation
    • 1,770
    Lipopolysaccharide causes an increase in intestinal tight junction permeability in vitro and in vivo by inducing enterocyte membrane expression and localization of TLR-4 and CD14.
    • 255