Interventricular mechanical asynchrony in pulmonary arterial hypertension: left-to-right delay in peak shortening is related to right ventricular overload and left ventricular underfilling.

@article{Marcus2008InterventricularMA,
  title={Interventricular mechanical asynchrony in pulmonary arterial hypertension: left-to-right delay in peak shortening is related to right ventricular overload and left ventricular underfilling.},
  author={Johannes Tim Marcus and Christiaan Tji-Joong Gan and Jaco J. M. Zwanenburg and A. L. Boonstra and Cor P Allaart and Marco J. W. G{\"o}tte and Anton Vonk-Noordegraaf},
  journal={Journal of the American College of Cardiology},
  year={2008},
  volume={51 7},
  pages={750-7}
}
OBJECTIVES The purpose of this study was to explore in pulmonary arterial hypertension (PAH) whether the cause of interventricular asynchrony lies in onset of shortening or duration of shortening. BACKGROUND In PAH, leftward ventricular septal bowing (LVSB) is probably caused by a left-to-right (L-R) delay in myocardial shortening. METHODS In 21 PAH patients (mean pulmonary arterial pressure 55 +/- 13 mm Hg and electrocardiogram-QRS width 100 +/- 16 ms), magnetic resonance imaging… CONTINUE READING

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