PURPOSE To prospectively investigate the efficacy of a wire basket extractor in the retrieval of salivary calculi and establish selection criteria for suitable cases. MATERIALS AND METHODS Twenty-five consecutive patients (14 male, 11 female; age range, 13-69 years) with salivary calculi (20 submandibular, five parotid) were treated by using a commercially available wire basket extractor with intermittent fluoroscopic guidance. RESULTS Elimination of calculi was accomplished in 10 (40%) cases. In an additional seven (28%) cases, either part of the calculus was removed or whole calculi were removed with others remaining. Failure to retrieve any stone occurred in eight (32%) cases. The most common cause of failure was attachment of the calculus to the duct wall. CONCLUSION Interventional radiology provides a useful adjuvant method of calculus removal and complements extracorporeal lithotripsy. Basket retrieval of calculi has low morbidity and is rapid and less invasive than traditional surgery. It is most effective in retrieving mobile stones in the extraglandular parotid and submandibular ducts.