Intersubject variability in the anticoagulant response to heparin in vitro


The significance of baseline coagulation times and plasma concentrations of serine protease inhibitors as determinants of the relationship between heparin activity and its anticoagulant effect has been investigated in vitro. Citrated plasma was prepared from blood obtained from 20 normal subjects, and heparin added to yield concentrations ranging from 0.05… (More)
DOI: 10.1007/BF00542044

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