Intersubject variability and reproducibility of 15O PET studies.

  title={Intersubject variability and reproducibility of 15O PET studies.},
  author={Jonathan P Coles and Tim D. Fryer and Peter Graham Bradley and Jurgens Nortje and Peter Smielewski and Kenneth Rice and John Connors Clark and John D. Pickard and David K. Menon},
  journal={Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism},
  volume={26 1},
Oxygen-15 positron emission tomography (15O PET) can provide important data regarding patients with head injury. We provide reference data on intersubject variability and reproducibility of cerebral blood flow (CBF), cerebral blood volume (CBV), cerebral metabolism (CMRO2) and oxygen extraction fraction (OEF) in patients and healthy controls, and explored alternative ways of assessing reproducibility within the context of a single PET study. In addition, we used independent measurements of CBF… CONTINUE READING