Interstitial pneumonitis, pulmonary fibrosis, and chronic graft-versus-host disease.

@article{Kaplan1992InterstitialPP,
  title={Interstitial pneumonitis, pulmonary fibrosis, and chronic graft-versus-host disease.},
  author={Ellen B Kaplan and Giuseppe G. Pietra and Charles S. August},
  journal={Bone marrow transplantation},
  year={1992},
  volume={9 1},
  pages={71-5}
}
Pneumonopathies in association with graft-versus-host disease (GVHD) are known, but the evolution of biopsy-proven interstitial pneumonitis (IP) to pulmonary fibrosis as a major pulmonary manifestation in an individual patient with chronic GVHD has not been previously reported. We present a patient with chronic GVHD who developed IP and then pulmonary fibrosis. We suggest that IP with evolution to pulmonary fibrosis was a major pulmonary manifestation of chronic GVHD in this patient.