Interstitial pO2 in ischemic penumbra and core are differentially affected following transient focal cerebral ischemia in rats.

@article{Liu2004InterstitialPI,
  title={Interstitial pO2 in ischemic penumbra and core are differentially affected following transient focal cerebral ischemia in rats.},
  author={Shimin Liu and Honglian Shi and Wenlan Liu and Takamitsu Furuichi and Graham S. Timmins and Ke Jian Liu},
  journal={Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism},
  year={2004},
  volume={24 3},
  pages={343-9}
}
Stroke causes heterogeneous changes in tissue oxygenation, with a region of decreased blood flow, the penumbra, surrounding a severely damaged ischemic core. Treatment of acute ischemic stroke aims to save this penumbra before its irreversible damage by continued ischemia. However, effective treatment remains elusive due to incomplete understanding of processes leading to penumbral death. While oxygenation is central in ischemic neuronal death, it is unclear exactly what actual changes occur in… CONTINUE READING
52 Extracted Citations
0 Extracted References
Similar Papers

Citing Papers

Publications influenced by this paper.
Showing 1-10 of 52 extracted citations

Similar Papers

Loading similar papers…