Interstitial hypertrophic neuropathy. Biochemical study of the peripheral nervous system.

@article{Koeppen1971InterstitialHN,
  title={Interstitial hypertrophic neuropathy. Biochemical study of the peripheral nervous system.},
  author={Arnulf H. Koeppen and H Messmore and William E. Stehbens},
  journal={Archives of neurology},
  year={1971},
  volume={24 4},
  pages={
          340-52
        }
}
Peripheral nerve tissue of a patient with an electron microscopically verified interstitial hypertrophic neuropathy contained excessive amounts of water and protein but less lipid than comparable control tissue. In the tissue hydrolyzate, hydroxyproline was increased fourfold, hexosamines, twofold. The reduction of lipid was associated with higher than normal levels of cholesteryl esters. The fatty acid profile of the triglycerides, cholesteryl esters, and phospholipids showed abnormally high… Expand
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