Interstitial exclusion of macromolecules studied by graded centrifugation of rat tail tendon.

@article{Aukland1997InterstitialEO,
  title={Interstitial exclusion of macromolecules studied by graded centrifugation of rat tail tendon.},
  author={Knut Aukland and Helge Wiig and Olav Tenstad and Eugene M. Renkin},
  journal={The American journal of physiology},
  year={1997},
  volume={273 6 Pt 2},
  pages={H2794-803}
}
Mechanical compression of cartilage and tendon has been shown to expel fluid both from collagen fibrils and from the extrafibrillar space. As reported previously, albumin (Alb) concentration and colloid osmotic pressure in tendon fluid (TF) expelled by repeated centrifugations fell progressively at increasing centrifugation force (G = 600, 2,400, and 13,100), suggesting either molecular sieving in compressed tendon or mobilization of protein-free (excluded) fluid. The present experiments… CONTINUE READING
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