Interstitial cells of Cajal: a new perspective on smooth muscle function.

@article{Sanders2006InterstitialCO,
  title={Interstitial cells of Cajal: a new perspective on smooth muscle function.},
  author={Kenton M. Sanders and Sean M Ward},
  journal={The Journal of physiology},
  year={2006},
  volume={576 Pt 3},
  pages={721-6}
}
Interstitial cells of Cajal (ICC) were described more than 100 years ago by Ramon y Cajal. For many years these cells were identified only by non-specific histological stains and later, more reliably, by electron microscopy. Ultrastructural features and the anatomical locations of ICC suggested important physiological roles for these cells. A breakthrough occurred in our ability to study ICC when it was recognized that antibodies for Kit could be used to identify ICC, even in living tissues… CONTINUE READING

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