Interspecies uncertainty in molecular responses and toxicity of mixtures.


Most of the experimental toxicity testing data for chemicals are generated through the use of laboratory animals, namely, rodents such as rats and mice or other species. Interspecies extrapolation is needed to nullify the differences between species so as to use such data for human health/risk assessment. Thus, understanding of interspecies differences is… (More)
DOI: 10.1007/978-3-7643-8340-4_12