Intersection of Iron and Copper Metabolism in the Mammalian Intestine and Liver.

@article{Doguer2018IntersectionOI,
  title={Intersection of Iron and Copper Metabolism in the Mammalian Intestine and Liver.},
  author={Caglar Doguer and Jung-Heun Ha and James F Collins},
  journal={Comprehensive Physiology},
  year={2018},
  volume={8 4},
  pages={
          1433-1461
        }
}
Iron and copper have similar physiochemical properties; thus, physiologically relevant interactions seem likely. Indeed, points of intersection between these two essential trace minerals have been recognized for many decades, but mechanistic details have been lacking. Investigations in recent years have revealed that copper may positively influence iron homeostasis, and also that iron may antagonize copper metabolism. For example, when body iron stores are low, copper is apparently… CONTINUE READING

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