Intersection of ChIP and FLIP, genomic methods to study the dynamics of the cohesin proteins

@article{McNairn2008IntersectionOC,
  title={Intersection of ChIP and FLIP, genomic methods to study the dynamics of the cohesin proteins},
  author={Adrian J. McNairn and Jennifer L Gerton},
  journal={Chromosome Research},
  year={2008},
  volume={17},
  pages={155-163}
}
The evolutionarily conserved cohesin proteins Smc1, Smc3, Rad21 (Mcd1), and Scc3 function in the cohesin complex that provides the basis for chromosome cohesion and is involved in gene regulation. Understanding how these proteins link together the genome requires the use of whole-genome approaches to study the molecular mechanisms of these essential… CONTINUE READING