Interruptions of early cortical development affect limbic association areas and social behaviour in rats; possible relevance for neurodevelopmental disorders

@article{Talamini1999InterruptionsOE,
  title={Interruptions of early cortical development affect limbic association areas and social behaviour in rats; possible relevance for neurodevelopmental disorders},
  author={Lucia M. Talamini and Tineke Koch and Paul G. M. Luiten and Jaap M. Koolhaas and Jakob Korf},
  journal={Brain Research},
  year={1999},
  volume={847},
  pages={105-120}
}
Deficits in social behaviour are found in several neuropsychiatric disorders with a presumed developmental origin. Adequate social behaviour may rely importantly on the associative integration of new stimuli with previously stored, related information. The limbic allocortex, in particular the entorhinal region, is thought to support this kind of processing. Therefore, in the present study, gestating dams were treated with methylazoxymethanol acetate (MAM) on one of gestational days nine to… CONTINUE READING

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References

Publications referenced by this paper.
SHOWING 1-10 OF 53 REFERENCES

Pharmacologically induced damage in the entorhinal cortex alters behavior and brain NGF levels in young rats : a possible correlation with the development of schizophrenia - like deficits

L. M. Talamini Fiore, F. Angelucci, T. Koch, L. Aloe, J. Korf
  • Neuropharma - Ž . cology
  • 1999

Dissociable effects of selective lesions to hippocampal subsystems on exploratory behavior , contextual learn - Ž . ing , and spatial learning

R. C. Honey Good
  • Behav . Neurosci .
  • 1997

Lesions of the entorhinal cortex disrupt behavioral and neuronal responses to context change during extinction of discriminative avoidance be - Ž

H. Weible Freeman, J. Rossi, M. Gabriel
  • haviour , Exp . Brain Res .
  • 1997

The hippocampus and memory for orderly stimulus relations.

  • Proceedings of the National Academy of Sciences of the United States of America
  • 1997