Interruptin B induces brown adipocyte differentiation and glucose consumption in adipose-derived stem cells

@article{Kaewsuwan2016InterruptinBI,
  title={Interruptin B induces brown adipocyte differentiation and glucose consumption in adipose-derived stem cells},
  author={Sireewan Kaewsuwan and A. Plubrukarn and M. Utsintong and Seok-Ho Kim and Jin-Hyun Jeong and Jin Gu Cho and S. G. Park and Jong-Hyuk Sung},
  journal={Molecular Medicine Reports},
  year={2016},
  volume={13},
  pages={2078 - 2086}
}
Interruptin B has been isolated from Cyclosorus terminans, however, its pharamcological effect has not been fully identified. In the present study, the effects of interruptin B, from C. terminans, on brown adipocyte differentiation and glucose uptake in adipose-derived stem cells (ASCs) were investigated. The results revealed that interruptin B dose-dependently enhanced the adipogenic differentiation of ASCs, with an induction in the mRNA expression levels of peroxisome proliferator-activated… Expand
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