Interrupted time series analysis of vancomycin compared to cefuroxime for surgical prophylaxis in patients undergoing cardiac surgery.

@article{Garey2008InterruptedTS,
  title={Interrupted time series analysis of vancomycin compared to cefuroxime for surgical prophylaxis in patients undergoing cardiac surgery.},
  author={Kevin W Garey and Dejian Lai and Thanh K Dao-Tran and Layne O. Gentry and Loris Y. Hwang and Brian Robert Davis},
  journal={Antimicrobial agents and chemotherapy},
  year={2008},
  volume={52 2},
  pages={
          446-51
        }
}
The increased incidence of methicillin-resistant Staphylococcus aureus (MRSA), the emergence of community-acquired MRSA, and the continued high incidence of methicillin-resistant Staphylococcus epidermidis have required that certain institutions choose vancomycin for surgical prophylaxis. However, the data supporting the use of vancomycin for surgical prophylaxis are controversial. The purpose of this project was to assess the effect of the change from cefuroxime to vancomycin for surgical site… CONTINUE READING
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