Interregional spread in Spain of linezolid-resistant Enterococcus spp. isolates carrying the optrA and poxtA genes.

@article{Moure2020InterregionalSI,
  title={Interregional spread in Spain of linezolid-resistant Enterococcus spp. isolates carrying the optrA and poxtA genes.},
  author={Z. Moure and N. Lara and M. Marín and P. J. Sola-Campoy and V. Bautista and F. G{\'o}mez-Bertomeu and Cristina G{\'o}mez-Dominguez and M. P{\'e}rez-V{\'a}zquez and B. Aracil and J. Campos and E. Cercenado and J. Oteo-Iglesias},
  journal={International journal of antimicrobial agents},
  year={2020},
  pages={
          105977
        }
}
The emergence of linezolid-resistant Enterococcus spp. (LRE) due to transferable resistance determinants is a matter of concern. To understand the contribution of the plasmid-encoded optrA and poxtA genes to the emergence of LRE, we analysed clinical isolates from different Spanish hospitals submitted to the Spanish Reference Laboratory from 2015-2018. Resistance mechanisms to linezolid were screened in all isolates by PCR and sequencing. Genetic relatedness of all Enterococcus spp. carrying… Expand

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