Interpreting lung function data using 80% predicted and fixed thresholds misclassifies more than 20% of patients.

@article{Miller2011InterpretingLF,
  title={Interpreting lung function data using 80\% predicted and fixed thresholds misclassifies more than 20\% of patients.},
  author={Martin R Miller and Philip H. Quanjer and Maureen P Swanney and Gregg L Ruppel and Paul L. Enright},
  journal={Chest},
  year={2011},
  volume={139 1},
  pages={
          52-9
        }
}
BACKGROUND Differences in COPD classification have been shown in population data sets when using fifth percentiles as the lower limit of normal (LLN) vs the current GOLD (Global Initiative for Chronic Obstructive Lung Disease) guidelines of FEV(1)/FVC < 0.70 for detecting airway obstruction and an FEV(1) of 80% predicted for detecting and classifying the severity of COPD (GOLD/PP). Many lung function laboratories use 80% predicted to determine whether results are abnormal. Misclassification of… Expand
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