Interpretation of thyroid function tests

@article{Dayan2001InterpretationOT,
  title={Interpretation of thyroid function tests},
  author={Colin M. Dayan},
  journal={The Lancet},
  year={2001},
  volume={357},
  pages={619-624}
}
  • C. Dayan
  • Published 24 February 2001
  • Medicine, Biology
  • The Lancet
View on Elsevier
keck.usc.edu
149 Citations
Highly Influential Citations
10
Background Citations
38
Methods Citations
8
Results Citations
1

149 Citations

Interpretation of thyroid function tests
Thyroid function tests are one of the most common endocrine panels in general practice because a good understanding of when to order them, interpretation of their results and indications for…
Thyroid function tests and its interpretation
TLDR
In the patients with obvious features of hypothyroidism or hyperthyroidism thyroid function tests only confirm the diagnosis, though TSH is widely used as a screening test in suspicion with thyroid disorder, many times TSH alone may be misleading.
Should Free Thyroxine Go Back into the Routine Thyroid Profile?
TLDR
The cost of identifying pituitary insufficiency by measuring both fT4 and TSH was estimated for the population (in 2004 and 2013) and compared with 2 other relevant studies and has become cheaper with time.
Laboratory tests of thyroid function: pitfalls in interpretation
When the clinical suspicion is strong (e.g. in a patient who exhibits overt symptoms and signs of hyperthyroidism), thyroid function tests are helpful in confirming the diagnosis. However, situations…
Optimization of the thyroid panel for diagnostic purposes: Thyrotropin cut-off values for the reflex addition of free thyroxine.
Thyrotropin isoforms: implications for thyrotropin analysis and clinical practice.
TLDR
This review focuses on the dissociation between the clinical state and serum TSH concentrations and addresses clinically important aspects of TSH analysis.
Interpretation of Thyroid Function Tests and Their Relationship to Iodine Nutrition: Changes in TSH, Free T4, and Free T3 Resulting from Iodine Deficiency and Iodine Excess
Unexpected Elevated Free Thyroid Hormones in Pregnancy
TLDR
A 35-year-old woman with a known diagnosis of chronic autoimmune thyroiditis was referred to the authors' clinic at week 26 of her second pregnancy, and was clinically euthyroid.
UPDATE ON THYROID DISORDERS
The thyroid gland regulates metabolism, therefore thyroid dysfunction has an impact throughout the body In iodine-replete areas, autoimmune disease is the commonest cause of thyroid disorders Thyroid…
Management of subclinical hypothyroidism.
TLDR
Patients with symptoms suggestive of hypothyroidism and those patients with thyroid-stimulating hormone (TSH) levels higher than 10 μIU per mL (10 mIU per L) or positive anti-thyroid peroxidase (TPO) antibodies are treated with levothyroxine.
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References

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The following Special Report from the Committee on Nomenclature of the American Thyroid Association (A TA) is an attempt to clarify some of the confusion that exists on the use and performance of the…
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TLDR
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Two patients with familial dysalbuminaemic hyperthyroxinaemia (FDH) are described in whom the albumin variant resulted in raised total T4 levels, and artefactually raised free T4 using a…
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TLDR
It is suggested that measurement of thyrotropin by an assay with improved detection limits will aid in correctly determining thyroid status, and the presence of thyroid hormone antibodies should be suspected when results of thyroid-function tests are discordant with the clinical state.
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TLDR
The results indicate that congenital primary hypothyroidism associated with TSH unresponsiveness is unlikely to be due to mutations in the TSHR-structure gene.
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TLDR
Variations in major thyroid hormone transport proteins may be inherited or acquired and may be associated with changes in serum concentration of the proteins or their affinity for thyroid hormones, but changes in transthyretin and albumin are also observed.
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