Interpretation of substituent effects on 13C and 15N NMR chemical shifts in 6-substituted purines.

@article{Standara2011InterpretationOS,
  title={Interpretation of substituent effects on 13C and 15N NMR chemical shifts in 6-substituted purines.},
  author={Stanislav Standara and Kateřina Bouzkov{\'a} and Michal Straka and Zuzana Zacharov{\'a} and Michal Hocek and Jarom{\'i}r Marek and Radek Marek},
  journal={Physical chemistry chemical physics : PCCP},
  year={2011},
  volume={13 35},
  pages={15854-64}
}
A range of purine derivatives modified at position 6 of the basic purine skeleton exhibit a variety of biological activities. Several derivatives are used or tested nowadays for pharmacological treatments. The present work aims to analyze the effects of substituents on the electron distribution in the purine core as reflected by NMR chemical shifts. We… CONTINUE READING