Interpretation of oxygen disappearance curves measured in blood perfused tissues.

@article{Buerk1986InterpretationOO,
  title={Interpretation of oxygen disappearance curves measured in blood perfused tissues.},
  author={Donald G. Buerk and Pretep K. Nair and Eileen Bridges and Tim Hanley},
  journal={Advances in experimental medicine and biology},
  year={1986},
  volume={200},
  pages={151-61}
}
We have developed a two compartment (tissue and blood) lumped parameter model to interpret oxygen disappearance curves (O2 DCs) measured in vivo with PO2 microelectrodes in tissues which are perfused with blood. To include the properties of the oxyhemoglobin equilibrium curve (HEC), we used an algorithm we have recently developed for both standard and nonstandard conditions. The new blood and tissue model is more useful than a previous analysis using the Hill equation for blood and constant… CONTINUE READING