Interpretation of alpha-fetoprotein concentrations in cerebrospinal fluid of infants.

@article{Coakley2005InterpretationOA,
  title={Interpretation of alpha-fetoprotein concentrations in cerebrospinal fluid of infants.},
  author={John Coakley and Stewart J. Kellie and Christa Ellen Nath and A Munas and Claire Cooke-Yarborough},
  journal={Annals of clinical biochemistry},
  year={2005},
  volume={42 Pt 1},
  pages={24-9}
}
BACKGROUND There are no published reference intervals for concentrations of alpha-fetoprotein (AFP) in the cerebrospinal fluid (CSF) of normal infants. The presence of abnormal concentrations of AFP in plasma or CSF may indicate the presence of a teratoma or a germ cell tumour with yolk sac elements. We measured CSF AFP in infants who did not have malignancy in order to determine its reference intervals. METHODS AFP was measured in the CSF and/or plasma in 128 infants. Of these, 91 infants… CONTINUE READING