Interpretation of ³¹P NMR saturation transfer experiments: what you can't see might confuse you. Focus on "Standard magnetic resonance-based measurements of the Pi→ATP rate do not index the rate of oxidative phosphorylation in cardiac and skeletal muscles".

@article{Balaban2011InterpretationO,
  title={Interpretation of ³¹P NMR saturation transfer experiments: what you can't see might confuse you. Focus on "Standard magnetic resonance-based measurements of the Pi→ATP rate do not index the rate of oxidative phosphorylation in cardiac and skeletal muscles".},
  author={Robert S Balaban and Alan P. Koretsky},
  journal={American journal of physiology. Cell physiology},
  year={2011},
  volume={301 1},
  pages={
          C12-5
        }
}
THE MEASUREMENT OF UNIDIRECTIONAL RATES of reaction, in vivo, using magnetization transfer techniques is a unique capability of nuclear magnetic resonance spectroscopy (NMRS). However, the complicated network of cytosolic reactions as well as the potential existence of small exchanging metabolic pools or enzyme-substrate complexes with poorly defined NMRS properties makes the interpretation of these data difficult. From and Ugurbil (14), in this issue, discuss using NMRS for analyzing the… CONTINUE READING

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