Interplay of tumor microenvironment cell types with parenchymal cells in pancreatic cancer development and therapeutic implications.

@article{Guturu2009InterplayOT,
  title={Interplay of tumor microenvironment cell types with parenchymal cells in pancreatic cancer development and therapeutic implications.},
  author={Praveen Guturu and Vijay Shah and Raul A Urrutia},
  journal={Journal of gastrointestinal cancer},
  year={2009},
  volume={40 1-2},
  pages={1-9}
}
INTRODUCTION The process of "induction," namely, the formation of a tissue by the functional interaction between the epithelial layer and the stroma, is key for the development of many organs, in particular to the pancreas. DISCUSSION In diseases like pancreatic cancer, most studies performed to date, in the area of pancreatic cancer, have focused on studying epithelial cells and their contribution to this disease. Strikingly, until recently, the stroma that surrounds cancer cells in… CONTINUE READING
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