Interplay of estrogen receptors and FOXA factors in the liver cancer.


Liver cancer is the fifth most common cancer in human with male dominance. Sexual dimorphism of liver cancer is conserved from rodents to humans, which was firstly found in mice in late 1930s and female mice were resistant to liver cancer. Sex hormones were found to affect the incidence of liver cancer in rodents. Estrogen receptor alpha (ERα)-mediated… (More)
DOI: 10.1016/j.mce.2015.01.043