Interplay between the temporal dynamics of the vaginal microbiota and human papillomavirus detection.

@article{Brotman2014InterplayBT,
  title={Interplay between the temporal dynamics of the vaginal microbiota and human papillomavirus detection.},
  author={Rebecca M Brotman and Michelle D Shardell and Pawel Gajer and J. Kathleen Tracy and Jonathan M. Zenilman and Jacques Ravel and Patti Gravitt},
  journal={The Journal of infectious diseases},
  year={2014},
  volume={210 11},
  pages={1723-33}
}
BACKGROUND We sought to describe the temporal relationship between vaginal microbiota and human papillomavirus (HPV) detection. METHODS Thirty-two reproductive-age women self-collected midvaginal swabs twice weekly for 16 weeks (937 samples). Vaginal bacterial communities were characterized by pyrosequencing of barcoded 16S rRNA genes and clustered into 6 community state types (CSTs). Each swab was tested for 37 HPV types. The effects of CSTs on the rate of transition between HPV-negative and… CONTINUE READING
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