Interplay between oxidative stress and immunity in the progression of alcohol-mediated liver injury.

@article{Vidali2008InterplayBO,
  title={Interplay between oxidative stress and immunity in the progression of alcohol-mediated liver injury.},
  author={Matteo Vidali and Stephen F Stewart and Emanuele Albano},
  journal={Trends in molecular medicine},
  year={2008},
  volume={14 2},
  pages={63-71}
}
Inflammation is recognized increasingly as having an important role in the pathogenesis of alcoholic liver disease (ALD). Nonetheless, the mechanisms by which alcohol maintains hepatic inflammation are still characterized incompletely. Several studies have demonstrated that ethanol-induced oxidative stress promotes immune responses in ALD by stimulating both humoral and cellular reactions against liver proteins adducted to hydroxyethyl free radicals and several lipid peroxidation products… CONTINUE READING
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