Interplay between dietary inducers of GST and the GSTM-1 genotype in colon cancer.

@article{Slattery2000InterplayBD,
  title={Interplay between dietary inducers of GST and the GSTM-1 genotype in colon cancer.},
  author={Martha L. Slattery and Ellen Kampman and Wade S. Samowitz and Bette Jane Caan and John D. Potter},
  journal={International journal of cancer},
  year={2000},
  volume={87 5},
  pages={
          728-33
        }
}
The purpose of this study is to determine if cruciferous vegetables and coffee, two dietary inducers of glutatione-S-transferases, interact with GSTM-1 genotype to alter risk of colon cancer. Data were available on 1579 incident cases of adenocarcinoma of the colon and 1898 population-based controls. Intake of cruciferous vegetables, specific types of cruciferous vegetable, and coffee were not associated with colon cancer; GSTM-1 genotype did not modify these associations. However, age at… CONTINUE READING
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