Interplay between diet-induced obesity and chronic stress in mice: potential role of FKBP51.

  title={Interplay between diet-induced obesity and chronic stress in mice: potential role of FKBP51.},
  author={Georgia Balsevich and Andr{\'e}s Uribe and Klaus V. Wagner and Jakob Hartmann and Sara Santarelli and Christiana Labermaier and Mathias V Schmidt},
  journal={The Journal of endocrinology},
  volume={222 1},
While it is known that stress promotes obesity, the effects of stress within an obesogenic context are not so clear and molecular targets at the interface remain elusive. The FK506-binding protein 51 (FKBP51, gene: Fkbp5) has been identified as a target gene implicated in the development of stress-related psychiatric disorders and is a possible candidate for involvement in stress and metabolic regulation. The aims of the current study are to investigate the interaction between chronic stress… CONTINUE READING
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