Interplay between cost and benefits triggers nontrivial vaccination uptake

  title={Interplay between cost and benefits triggers nontrivial vaccination uptake},
  author={Benjamin Steinegger and Alessio Cardillo and Paolo De Los Rios and Jes{\'u}s G{\'o}mez-Garde{\~n}es and Alex Arenas},
  journal={Physical Review. E},
The containment of epidemic spreading is a major challenge in science. Vaccination, whenever available, is the best way to prevent the spreading, because it eventually immunizes individuals. However, vaccines are not perfect, and total immunization is not guaranteed. Imperfect immunization has driven the emergence of antivaccine movements that totally alter the predictions about the epidemic incidence. Here, we propose a mathematically solvable mean-field vaccination model to mimic the… 

Figures from this paper

Competition between vaccination and disease spreading.

The interaction between epidemic spreading and a vaccination process is studied in the framework of mean-field theory finding a rich phase diagram and Numerical simulations for homogeneous random networks agree very well with analytical predictions.

Interplay between cost and effectiveness in influenza vaccine uptake: a vaccination game approach

The approach presumes a mean-field framework of a vaccination game in an infinite and well-mixed population, entangling the disease spreading process of influenza with the coevolution of two types of vaccination decision-making processes taking place before an epidemic season.

Pulsating campaigns of human prophylaxis driven by risk perception palliate oscillations of direct contact transmitted diseases

Analytically, the interplay between the personal decision to protect oneself from infection and the spreading of an epidemic is explored, by coupling a decision game based on the perceived risk of infection with a Susceptible-Infected-Susceptible model.

Emergence of protective behaviour under different risk perceptions to disease spreading

The behaviour of individuals is a main actor in the control of the spread of a communicable disease and, in turn, the spread of an infectious disease can trigger behavioural changes in a population.

Markovian approach to tackle the interaction of simultaneous diseases.

A general and versatile benchmark to address the unfolding of both cooperative and competitive interacting diseases is proposed and the explosive transitions between the disease-free and the epidemic regimes arising from the cooperation between pathogens are characterized.

Impact of temporal scales and recurrent mobility patterns on the unfolding of epidemics

A Markovian framework is developed that enables an analytical expression for the epidemic threshold, capturing the critical conditions triggering epidemic outbreaks, and reveals that the impact of tuning human mobility on the emergence of diseases is strongly affected by the temporal scales associated to both epidemiological and mobility processes.

Vector-borne epidemics driven by human mobility

This work proposes a framework whose results are in fair agreement with those obtained from mechanistic simulations of the epidemic threshold capturing with high accuracy the conditions leading to the onset of epidemics.

Behavioural response to heterogeneous severity of COVID-19 explains temporal variation of cases among different age groups

A mechanistic explanation for the phenomenology attributable to a heterogeneous prophylaxis induced by the age-specific severity of the disease is provided and results indicate that the mixing of contacts among the age groups strongly determines the delay between their peaks in prevalence and the temporal variation in the distribution of cases.

Explosive transitions induced by interdependent contagion-consensus dynamics in multiplex networks.

A model to study the interplay between information spreading and opinion formation in social systems in which consensus is favored by the common adoption of information, while information spreading is boosted between agents sharing similar opinions is introduced.



Imperfect Vaccine Aggravates the Long-Standing Dilemma of Voluntary Vaccination

It is shown that increasing effectiveness of vaccination always increases the number of effectively vaccinated individuals and therefore attenuates the epidemic strain, and the results suggest that ‘number is traded for efficiency’: although increases in vaccination effectiveness lead to uptake drops due to free-riding effects, the impact of the epidemic can be better mitigated.

Imitation dynamics of vaccination behaviour on social networks

This work sheds light on how imitation of peers shapes individual vaccination choices in social networks, and integrates an epidemiological process into a simple agent-based model of adaptive learning, which suggests parallels to historical scenarios in which vaccination coverage provided herd immunity for some time, but then rapidly dropped.

Vaccination and the theory of games.

  • C. BauchD. Earn
  • Medicine
    Proceedings of the National Academy of Sciences of the United States of America
  • 2004
It is shown that a formal game theoretical analysis of the problem of whether a sufficient proportion of the population is already immune, either naturally or by vaccination, leads to new insights that help to explain human decision-making with respect to vaccination.

The Evolutionary Vaccination Dilemma in Complex Networks

In this work we analyze the evolution of voluntary vaccination in networked populations by entangling the spreading dynamics of an influenza-like disease with an evolutionary framework taking place

Statistical physics of vaccination

The Interplay of Public Intervention and Private Choices in Determining the Outcome of Vaccination Programmes

This work proposes a simple SIR transmission model with vaccination choice, and shows that public intervention has a stabilising role which is able to reduce the strength of imitation-induced oscillations, to allow disease elimination, and to even make the disease-free equilibrium where everyone is vaccinated globally attractive.

Epidemic spreading in multiplex networks influenced by opinion exchanges on vaccination

An epidemic threshold was found, in which below β* and above ω* the diseases never becomes an epidemic, and it varies with the opinion parameter r, which takes into account two different processes that occurs in a society: persuasion and compromise.

Evolutionary Game Theory and Social Learning Can Determine How Vaccine Scares Unfold

A model based on evolutionary game theory that captures feedback in the context of vaccine scares, and that also includes social learning and feedback is analyzed, which could help predict how vaccine scares might unfold and assist mitigation efforts.

On the benefits of explaining herd immunity in vaccine advocacy

Most vaccines protect both the vaccinated individual and the community at large by building up herd immunity. Even though reaching disease-specific herd immunity thresholds is crucial for eliminating